organized by Kathrin Ulrich and Elisa Motori
Upcoming speaker
June 6, 2024: Peter Kreuzaler
Cologne Excellence Cluster on Aging and Aging-Associated Diseases
Peter recently established his junior group at CECAD in Cologne. His work focuses on cancer metabolism and in this regard, he previously found a link between cancer progression and the need for Vitamin B5 uptake
June 19, 2024: Michal-Ruth Schweiger
Institute for Translational Epigenomics, University of Cologne
The main focus of the Schweiger lab is to understand the function of non-coding repetitive DNA under normal and pathological conditions. Repetitive regions are frequently hypomethylated in cancer and transcriptionally activated, which is one of the hallmarks of cancer and is associated with genomic instability and poor prognosis. Additionally, under diverse stress conditions, repetitive RNAs form membraneless nuclear stress bodies (nSBs). Using diverse specific and high-throughput technologies we try to understand why many oncogenic mutations occur in proteins located in nSBs and if there is a link to the expression of satellite RNAs which promotes disease development.